Insulin safety in clinical practice

This section is an introduction and literature review chapter in my dissertation. I have written around 2000 words but my supervisor have comments on it. So I need you to expand it.
Please see the attached file. Read file (1) first, then you can start editing and improving file (2) as I have added some comment of my supervisor between the texts and paragraphs. The word count limit (excluding the reference list) is up to 2500. It is acceptable to be 10% more but dont exceed 2700 words.
The reference: you can add from 4 to 8 references as appropriate.